Synthesis of bis-3,4-dialkoxythiophenes linked by am-xylene bridge

Cisneros Pérez, Pablo A.; Frontana Uribe, Bernardo A.; Martínez Otero, Diego; Cuevas Yáñez, Erick

dc.contributor.author	Cisneros Pérez, Pablo A.
dc.contributor.author	Frontana Uribe, Bernardo A.
dc.contributor.author	Martínez Otero, Diego
dc.contributor.author	Cuevas Yáñez, Erick
dc.date.accessioned	2019-06-06T20:45:45Z
dc.date.available	2019-06-06T20:45:45Z
dc.date.issued	2016
dc.identifier.citation	Cisneros-Pérez, P. A., Frontana-Uribe, B. A., Martínez-Otero, D., & Cuevas-Yáñez, E. (2016). Synthesis of bis-3,4-dialkoxythiophenes linked by a m-xylene bridge. Tetrahedron Letters, 57(46), 5089–5093. doi:10.1016/j.tetlet.2016.10.015.	es
dc.identifier.other	http://repositorio.ikiam.edu.ec:8080/jspui/handle/RD_IKIAM/169
dc.identifier.uri	http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/169
dc.identifier.uri	https://doi.org/10.1016/j.tetlet.2016.10.015
dc.description.abstract	Two examples of bis 3,4-dialkoxythiophenes linked with am-xylene bridge were synthesized in yields of18% and 32% in a six step process. The formation of them-xylene bridge, key reaction of the synthesis,was carried out through Williamson, Mitsunobu andtrans-etherification reactions which were subse-quently compared on performance and versatility. The Mitsunobu reaction assisted by sonication wasfound to be the best strategy. These molecules are among the few examples of unsymmetrically substi-tuted 3,4-dialcoxythiophenes. During the synthesis an 18 member heterocycle, closely related to a crownether was isolated. The details of the XRD structure of this heterocycle are discussed.	es
dc.language.iso	en	es
dc.publisher	Elsevier	es
dc.relation.ispartofseries	PRODUCCIÓN CIENTÍFICA-ARTÍCULOS;A-IKIAM-000106
dc.rights	Atribución-NoComercial-SinDerivadas 3.0 Estados Unidos de América	*
dc.rights	openAccess	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	3,4-Dialkoxythiophene	es
dc.subject	m-Xylene bridge	es
dc.subject	Unsymmetrical etherification	es
dc.subject	Ultrasound	es
dc.subject	p-Conjugated systems	es
dc.title	Synthesis of bis-3,4-dialkoxythiophenes linked by am-xylene bridge	es
dc.type	Article	es